A novel bioinformatic database has been established to facilitate more profound investigations into the genes associated with sexual dimorphism. This bioinformatics tool primarily facilitates the visualization of protein-coding gene expressions and variations across individual male and female samples. Users are encouaged to explore the variations in expression and the levels of protein-coding genes across a range of significant tissue subtypes utilizing the latest GTEx V10 datasets. An escalating focus on the importance of sexual dimorphism has emerged within clinical practices and biomedical research. A thorough comprehension of human biology in both sexes is crucial, given the inherent variations that exist within each. It is our conviction that the distinct variations between individuals of different sexes ought to be given greater prominence in the studies of sexual dimorphism. Furthermore, the expression of genes that demonstrate tissue-specific sexual dimorphism is widely acknowledged to have significant implications in a range of diseases. Our aim is to offer accessible assistance in the exploration of hypothetical human protein-coding genes that play a role in human variations and the study of sexual dimorphism.

---

By Gene Symbol

Gene Symbol : 

Tissue :  Select adipose_subcutaneous adipose_visceral_omentum adrenal_gland artery_aorta artery_coronary artery_tibial bladder brain_amygdala brain_anterior_cingulate_cortex_ba24 brain_caudate_basal_ganglia brain_cerebellar_hemisphere brain_cerebellum brain_cortex brain_frontal_cortex_ba9 brain_hippocampus brain_hypothalamus brain_nucleus_accumbens_basal_ganglia brain_putamen_basal_ganglia brain_spinal_cord_cervical_c-1) brain_substantia_nigra breast_mammary_tissue colon_sigmoid colon_transverse esophagus_gastroesophageal_junction esophagus_mucosa esophagus_muscularis heart_atrial_appendage heart_left_ventricle kidney_cortex liver lung minor_salivary_gland muscle_skeletal nerve_tibial pancreas pituitary skin_not_sun_exposed_suprapubic skin_sun_exposed_lower_leg small_intestine_terminal_ileum spleen stomach thyroid whole_blood

Submit

---

By Tissue & Z-score

Gene Expression TPM :  0.1 0.5 1.0

Chromosome :  1~22 XY

Z-score cutoff :  1.96 2.58

Cardiovascular: ▼
Artery_Aorta Z-score M ≤ F Z-score M ≥ F Artery_Coronary Z-score M ≤ F Z-score M ≥ F Artery_Tibial Z-score M ≤ F Z-score M ≥ F Heart_Atrial Appendage Z-score M ≤ F Z-score M ≥ F Heart_Left Ventricle Z-score M ≤ F Z-score M ≥ F

Digestion:        ▼

Liver Z-score M ≤ F Z-score M ≥ F Minor Salivary Gland Z-score M ≤ F Z-score M ≥ F Esophagus_Gastroesophageal Junction Z-score M ≤ F Z-score M ≥ F Esophagus_Mucosa Z-score M ≤ F Z-score M ≥ F Esophagus_Muscularis Z-score M ≤ F Z-score M ≥ F Stomach Z-score M ≤ F Z-score M ≥ F Small Intestine_Terminal ileum Z-score M ≤ F Z-score M ≥ F Colon_Sigmoid Z-score M ≤ F Z-score M ≥ F Colon_Transverse Z-score M ≤ F Z-score M ≥ F

Endocrine:       ▼
Thyroid Z-score M ≤ F Z-score M ≥ F Pancreas Z-score M ≤ F Z-score M ≥ F Pituitary Z-score M ≤ F Z-score M ≥ F Adrenal Gland Z-score M ≤ F Z-score M ≥ F

Integumentary:         ▼
Skin_Not Sun Exposed Z-score M ≤ F Z-score M ≥ F Skin_Sun Exposed Z-score M ≤ F Z-score M ≥ F Adipose_Subcutaneous Z-score M ≤ F Z-score M ≥ F Adipose_Visceral Z-score M ≤ F Z-score M ≥ F

Lymphatic:           ▼
Spleen Z-score M ≤ F Z-score M ≥ F Whole Blood Z-score M ≤ F Z-score M ≥ F

Nervous: ▼

Brain_Amygdala Z-score M ≤ F Z-score M ≥ F Brain_Anterior Cingulate cortex Z-score M ≤ F Z-score M ≥ F Brain_Caudate Z-score M ≤ F Z-score M ≥ F Brain_Cerebellar Hemisphere Z-score M ≤ F Z-score M ≥ F Brain_Cerebellum Z-score M ≤ F Z-score M ≥ F Brain_Cortex Z-score M ≤ F Z-score M ≥ F Brain_Frontal Cortex Z-score M ≤ F Z-score M ≥ F Brain_Hippocampus Z-score M ≤ F Z-score M ≥ F Brain_Hypothalamus Z-score M ≤ F Z-score M ≥ F Brain_Nucleus accumbens Z-score M ≤ F Z-score M ≥ F Brain_Putamen Z-score M ≤ F Z-score M ≥ F Brain_Spinal cord Z-score M ≤ F Z-score M ≥ F Brain_Substantia nigra Z-score M ≤ F Z-score M ≥ F Nerve_Tibial Z-score M ≤ F Z-score M ≥ F

Muscle: ▼
Muscle_Skeletal Z-score M ≤ F Z-score M ≥ F

Respiratory:   ▼
Lung Z-score M ≤ F Z-score M ≥ F

Reproductive:   ▼
Breast_Mammary Tissue Z-score M ≤ F Z-score M ≥ F

Urinary:           ▼
Kidney Cortex Z-score M ≤ F Z-score M ≥ F Bladder Z-score M ≤ F Z-score M ≥ F

---

By Numbers of Tissues